Repository Corticotherapy in Ophthalmic Theory and Practice.

IN repository corticotherapy a quantity of long-acting steroid is placed directly into the tissues; in ophthalmology, by reason of the delicacy of the tissues concerned, the steroid preparation used must not cause any damage when it is forced into the tissues, or later, and at the same time must retain its potency throughout the period of absorption. It is claimed by the manufacturers that Depo-Medrone (methylprednisolone acetate, Upjohn) fulfils these criteria. Clearly, this type of treatment will have a number of advantages in ophthalmic practice; for example, it will be preferable where locally administered steroids are impracticable, or when systemic steroids are dangerous by reason of systemic disease or emotional instability. These points will be enlarged upon later.